Please use this identifier to cite or link to this item: http://hdl.handle.net/10316/84317
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dc.contributor.authorMamede, A. P.-
dc.contributor.authorVassalo, A. R.-
dc.contributor.authorCunha, E.-
dc.contributor.authorGonçalves, D.-
dc.contributor.authorParker, S. F.-
dc.contributor.authorCarvalho, L. A. E. Batista de-
dc.contributor.authorMarques, M. P. M.-
dc.date.accessioned2019-01-24T11:25:24Z-
dc.date.available2019-01-24T11:25:24Z-
dc.date.issued2018-
dc.identifier.urihttp://hdl.handle.net/10316/84317-
dc.description.abstractTwo different deproteination and defatting processes of human bone were investigated, by combined infrared and neutron techniques: a previously reported hydrazine extraction and a newly developed multi-enzymatic treatment. Complementary Fourier transform infrared total attenuated reflectance and inelastic neutron scattering spectroscopies were applied, allowing access to all vibrational modes of the samples. The effectiveness of the different experimental protocols for removing the organic constituents of bone (lipids and protein) was probed, as well as their effect on bone's structural and crystallinity features. The results thus gathered are expected to have an impact on bioanthropological, archaeological and medical sciences, namely regarding the development of novel biocompatible materials for orthopaedic xenografts.pt
dc.language.isoporpt
dc.rightsopenAccesspt
dc.titleBiomaterials from human bone – probing organic fraction removal by chemical and enzymatic methodspt
dc.typearticle-
degois.publication.firstPage27260pt
degois.publication.lastPage27267pt
degois.publication.issue48pt
dc.peerreviewedyespt
dc.identifier.doi10.1039/C8RA05660Apt
degois.publication.volume8pt
dc.date.embargo2018-01-01*
dc.date.periodoembargo0pt
uc.controloAutoridadeSim-
item.languageiso639-1pt-
item.fulltextCom Texto completo-
item.grantfulltextopen-
crisitem.author.deptFaculty of Sciences and Technology-
crisitem.author.deptFaculty of Sciences and Technology-
crisitem.author.deptFaculty of Sciences and Technology-
crisitem.author.deptFaculty of Sciences and Technology-
crisitem.author.parentdeptUniversity of Coimbra-
crisitem.author.parentdeptUniversity of Coimbra-
crisitem.author.parentdeptUniversity of Coimbra-
crisitem.author.parentdeptUniversity of Coimbra-
crisitem.author.researchunitCFE - Centre for Functional Ecology - Science for People & the Planet-
crisitem.author.researchunitCIAS - Research Centre for Anthropology and Health-
crisitem.author.researchunitQFM-UC – Molecular Physical-Chemistry R&D Unit-
crisitem.author.researchunitQFM-UC – Molecular Physical-Chemistry R&D Unit-
crisitem.author.orcid0000-0003-2998-371X-
crisitem.author.orcid0000-0002-0607-5631-
crisitem.author.orcid0000-0002-8059-8537-
crisitem.author.orcid0000-0002-8391-0055-
Appears in Collections:I&D CIAS - Artigos em Revistas Internacionais
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