Please use this identifier to cite or link to this item: http://hdl.handle.net/10316/8415
Title: G2019S dardarin substitution is a common cause of Parkinson's disease in a Portuguese cohort
Authors: Brás, José Miguel 
Guerreiro, Rita João 
Ribeiro, Maria Helena 
Januário, Cristina 
Morgadinho, Ana 
Oliveira, Catarina Resende 
Cunha, Luís 
Hardy, John 
Singleton, Andrew 
Issue Date: 2005
Citation: Movement Disorders. 20:12 (2005) 1653-1655
Abstract: LRRK2 mutations have recently been described in families with Parkinson's disease. Here we show that one of them (G2019S) is present in 6% (7 of 124) unrelated cases of disease in a clinic-based sample series from central Portugal, but not present in 126 controls from the same population. Thus, LRRK2 mutations appear to be a common cause of typical Parkinson's disease and as such will alter clinical practice. © 2005 Movement Disorder Society
URI: http://hdl.handle.net/10316/8415
DOI: 10.1002/mds.20682
Rights: openAccess
Appears in Collections:FMUC Medicina - Artigos em Revistas Internacionais

Files in This Item:
File Description SizeFormat
obra.pdf69.5 kBAdobe PDFView/Open
Show full item record

SCOPUSTM   
Citations

80
checked on Feb 18, 2020

WEB OF SCIENCETM
Citations

77
checked on Feb 18, 2020

Page view(s) 50

412
checked on Apr 8, 2020

Download(s)

158
checked on Apr 8, 2020

Google ScholarTM

Check

Altmetric

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.