Please use this identifier to cite or link to this item: http://hdl.handle.net/10316/80879
Title: 2-Bromo-5-hydroxyphenylporphyrins for photodynamic therapy: photosensitization efficiency, subcellular localization and in vivo studies
Authors: Laranjo, Mafalda 
Serra, Arménio C 
Abrantes, Margarida 
Piñeiro, Marta 
Gonçalves, Ana C 
Casalta-Lopes, João 
Carvalho, Lina 
Sarmento-Ribeiro, Ana B 
Rocha-Gonsalves, António 
Botelho, Filomena 
Issue Date: Feb-2013
Issue Date: Feb-2013
Abstract: Photodynamic therapy (PDT) is a therapeutic modality capable of inducing cell death by oxidative stress through activation of a sensitizer by light. Aryl-porphyrin with hydroxyl groups are good photosensitizers and presence of bromine atoms can enhance the photodynamic activity through heavy atom effect. These facts and our previous work made pertinent to compare the photodynamic capacity of tetraaryl brominated porphyrin (TBr4) with the corresponding diaryl (BBr2) derivative.
URI: http://hdl.handle.net/10316/80879
ISSN: 1873-1597
DOI: 10.1016/j.pdpdt.2012.05.003
Rights: openAccess
Appears in Collections:FCTUC Química - Artigos em Revistas Internacionais

Files in This Item:
File Description SizeFormat
1-s2.0-S1572100012000683-main.pdf984.64 kBAdobe PDFView/Open
Show full item record

SCOPUSTM   
Citations

12
checked on Jun 25, 2019

WEB OF SCIENCETM
Citations

10
checked on Jun 25, 2019

Page view(s)

40
checked on Aug 21, 2019

Download(s)

33
checked on Aug 21, 2019

Google ScholarTM

Check

Altmetric

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.