Please use this identifier to cite or link to this item: http://hdl.handle.net/10316/100516
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dc.contributor.authorGalindres, Diana M.-
dc.contributor.authorCifuentes, Diego-
dc.contributor.authorTinoco, Luz Elena-
dc.contributor.authorMurillo-Acevedo, Yesid-
dc.contributor.authorRodrigo, M. Melia-
dc.contributor.authorRibeiro, Ana C. F.-
dc.contributor.authorEsteso, Miguel A.-
dc.date.accessioned2022-06-28T09:01:04Z-
dc.date.available2022-06-28T09:01:04Z-
dc.date.issued2022-
dc.identifier.issn2227-9717pt
dc.identifier.urihttp://hdl.handle.net/10316/100516-
dc.description.abstractDue to the diseases that people face today, scientists dedicate a part of their research to the synthesis, characterization, and study of functional compounds for controlled drug delivery. On the one hand, resorcinarenes are macrocycles obtained by condensation reactions of resorcinol and aldehyde. They include an upper and a lower rim functioning with different groups that confer solubility to the macrocycle and favor interactions with other compounds, therefore the hydroxyl groups on the upper rim improve the formation of hydrogen bonds. Additionally, resorcinarenes feature a cavity studied for forming host-guest complexes. SBA-15, on the other hand, is a mesoporous silica characterized by ordered pores in its structure and a large surface area. As a result of its properties, it has been used for several purposes, including absorbents, drug delivery, catalysis, and environmental processes. This review shows the recent advances in synthesis methods, characterization, micelle formation, interaction with other compounds, and host-guest procedures, as well as techniques for evaluating toxicity, drug retention, and their preliminary uses in pharmacology for macrocycles, such as resorcin[4]arenes and SBA-15.pt
dc.language.isoengpt
dc.relationFundación Universidad de América (Bogotá, Colombia), project: “Articulación de las Ciencias Básicas y la Ingeniería desde la química y el análisis de modelos matemáticos y de aprendizaje autónomopt
dc.relationUniversity of Alcalá (Spain), Program: “Stays for Foreign Scientists and Technologists—2021"pt
dc.rightsopenAccesspt
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt
dc.subjectresorcin[4]arenespt
dc.subjectSBA-15pt
dc.subjectmacrocyclespt
dc.subjectpharmacologypt
dc.subjectdrug deliverypt
dc.subjectmesoporous silicapt
dc.subjectadsorbentspt
dc.subjecthost-guest complexpt
dc.titleA Review of the Application of Resorcinarenes and SBA-15 in Drug Deliverypt
dc.typearticle-
degois.publication.firstPage684pt
degois.publication.issue4pt
degois.publication.titleProcessespt
dc.peerreviewedyespt
dc.identifier.doi10.3390/pr10040684pt
degois.publication.volume10pt
dc.date.embargo2022-01-01*
uc.date.periodoEmbargo0pt
item.grantfulltextopen-
item.fulltextCom Texto completo-
item.languageiso639-1en-
crisitem.author.deptFaculty of Sciences and Technology-
crisitem.author.parentdeptUniversity of Coimbra-
crisitem.author.researchunitCQC - Coimbra Chemistry Centre-
crisitem.author.researchunitCQC - Coimbra Chemistry Centre-
crisitem.author.parentresearchunitFaculty of Sciences and Technology-
crisitem.author.parentresearchunitFaculty of Sciences and Technology-
crisitem.author.orcid0000-0002-3005-1963-
crisitem.author.orcid0000-0001-9736-3999-
Appears in Collections:I&D CQC - Artigos em Revistas Internacionais
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